Formal:
* Avez-vous des frères et sœurs? (Do you have brothers and sisters?)
* Avez-vous des siblings? (Do you have siblings?)
Informal:
* Tu as des frères et sœurs? (Do you have brothers and sisters?)
* T'as des frères et sœurs? (More casual, literally "You have brothers and sisters?")
* Tu as des siblings? (Do you have siblings?)
Note: While "siblings" is a perfectly acceptable English word, it's less common in everyday French conversation. "Frères et sœurs" is the more usual phrase.