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What is the definition of a confirmatory test?

A confirmatory test is a diagnostic test used to verify or confirm the results of a preliminary or screening test.

Here's a breakdown:

* Preliminary test: This is the initial test used to screen for a particular condition or substance. It's often quick and inexpensive but may not be entirely accurate.

* Confirmatory test: This is a more specific and sensitive test used to validate the results of the preliminary test. It provides a higher level of certainty about the presence or absence of the target condition or substance.

Key features of a confirmatory test:

* Higher specificity: It accurately identifies individuals who do have the condition or substance, minimizing false positives.

* Higher sensitivity: It accurately identifies individuals who don't have the condition or substance, minimizing false negatives.

* More accurate results: Confirmatory tests provide a higher level of confidence in the diagnosis.

Examples of confirmatory tests:

* HIV confirmation: After a positive initial HIV test, a confirmatory test is used to confirm the diagnosis.

* Drug testing: A urine test may be used as a preliminary screening for drugs. A confirmatory test, such as a gas chromatography-mass spectrometry (GC-MS) test, is then used to confirm the presence of specific drugs.

* Pregnancy testing: A home pregnancy test can be used as a preliminary screen. A confirmatory test, such as a blood test, can provide a more accurate diagnosis.

In summary, a confirmatory test is crucial for ensuring accurate diagnosis and treatment by providing a more reliable and definitive result than a preliminary test alone.

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