How do you know which way to spell course as in of and what are the two ways course?

You're right, there are two ways to spell "course" when it means "of" or "in the course of." They are:

* Of course: This is the common phrase meaning "certainly" or "naturally." It is always spelled with two words.

* In course of: This phrase means "during" or "as part of." It is always spelled with two words.

Remember:

* "Of course" is always two words.

* "In course of" is always two words.

Let me know if you have any other spelling questions!