Simple:
* The children giggled as they played hide-and-seek.
* She couldn't help but giggle at his silly joke.
Descriptive:
* A nervous giggle escaped her lips as she waited for her turn.
* The sound of their playful giggles filled the room.
* Her eyes twinkled with amusement as she let out a soft giggle.
Figurative:
* The wind giggled through the trees, rustling the leaves.
* The brook giggled its way down the mountainside.
With a specific person:
* He gave her a playful nudge and she giggled in response.
* The baby giggled with delight as her mother tickled her.
In a dialogue:
* "I can't believe you forgot your keys again!" she said, trying to stifle a giggle.
* "Don't worry," he said, with a mischievous giggle, "I'll let myself in."
You can also use "giggle" as a noun:
* Her giggle was contagious.
* A wave of giggles swept through the audience.
The best way to use "giggle" depends on the context and the desired effect.