Here are some examples of how to use "despicable" in a sentence:
* His betrayal of his friends was a despicable act. (This sentence uses "despicable" to describe a morally reprehensible act.)
* The villain's plan to destroy the city was utterly despicable. (Here, "despicable" emphasizes the evil nature of the villain's plan.)
* The way he treated her was despicable, and I couldn't believe he would be so cruel. (This sentence uses "despicable" to highlight the cruelty and inhumanity of someone's behavior.)
Remember, "despicable" is used to describe something that is extremely unpleasant, morally wrong, and worthy of contempt.