As a noun:
* The teacher suspected Timmy was the troublemaker behind the missing crayons.
* She was known as a troublemaker in her youth, but she has matured considerably.
* The troublemaker in the back of the class was constantly disrupting the lesson.
As an adjective:
* The troublemaker student was sent to the principal's office.
* He had a troublemaker streak that often got him into trouble.
In a figurative sense:
* The new policy was seen as a troublemaker for the company.
* That song is a troublemaker – it gets stuck in my head all day!
The context of the sentence will determine the best way to use the word "troublemaker."