If "use" means "to put something to work or purpose":
* Disuse: To not be used or employed.
* Neglect: To fail to care for or use something.
* Abandonment: To stop using something completely.
* Waste: To use something inefficiently or without purpose.
If "use" refers to the act of employing something:
* Avoidance: To deliberately refrain from using something.
* Rejection: To refuse to use something.
* Disregard: To ignore or not consider something.
If "use" means "to consume something":
* Conservation: To use something sparingly or in a sustainable way.
* Preservation: To protect something from being used or depleted.
Ultimately, the best antonym for "use" depends on the specific context in which the word is used.