Think of it like the title of a book, except that in an encyclopedia, the "book" is the entire entry about that topic. For example, in an encyclopedia entry about "Elephants," the main heading would be "Elephants" in boldface, followed by all the information about elephants.
Here are some examples of main headings in encyclopedias:
* World War II
* Albert Einstein
* Photography
* DNA
* Ancient Egypt
The main heading is the key to finding information within the encyclopedia. It helps readers quickly identify the topic they're interested in and locate the relevant entry.