* Portuguese: Spoken in Brazil, the largest country in South America.
* English: Spoken in Guyana and Suriname.
* Dutch: Spoken in Suriname.
* French: Spoken in French Guiana.
* Quechua: Spoken in Peru, Bolivia, Ecuador, and parts of Argentina and Chile.
* Aymara: Spoken in Bolivia and Peru.
* Guarani: Spoken in Paraguay, Bolivia, and parts of Argentina and Brazil.
* Mapudungun: Spoken in Chile and Argentina.
* Many indigenous languages: There are hundreds of indigenous languages spoken in South America, each with its own unique history and culture.
It's important to note that even within a country, different languages and dialects can be spoken. For example, in Colombia, Spanish is the official language, but there are also several indigenous languages spoken, such as Wayuu and Embera.
Therefore, it's difficult to say definitively what "most South Americans speak," as the language landscape is complex and varied.