Formal:
* Como estão hoje, ambos? (This is the most formal and direct translation.)
* Como vão vocês hoje? (This is slightly less formal than the first option.)
Informal:
* E aí, tudo bem com vocês dois? (This is a casual and friendly way to say it.)
* Tudo sussa com vocês dois? (This is a very informal and slangy way to say it, meaning "Everything cool with you two?")
Note:
* You can also use "vocês" (you plural) instead of "ambos" (both of you) in the formal options, but "ambos" emphasizes that you are talking to both of them.
* In informal situations, it's common to use just "tudo bem?" or "tudo sussa?" without specifying "both of you" since it's implied by the context.
The best way to choose the right phrase depends on the context and your relationship with the people you are talking to.