* Sumerian: This was the earliest known written language in the world and was spoken in southern Mesopotamia (Sumer). While it eventually died out, its influence on Akkadian (see below) was significant.
* Akkadian: This Semitic language became dominant in Mesopotamia around the 23rd century BC. It had two main dialects: Babylonian and Assyrian. Akkadian remained the lingua franca of Mesopotamia for centuries and was used for administration, literature, and diplomacy.
Other languages spoken in Mesopotamia included:
* Eblaite: A Semitic language spoken in the city of Ebla.
* Hurrian: A non-Semitic language spoken by the Hurrians, a people who lived in northern Mesopotamia.
* Elamite: A language spoken by the Elamites, a people who lived in western Iran, who had significant influence on Mesopotamia.
It's important to note that these are just some of the more well-known languages spoken in Mesopotamia. There were many other languages spoken by different groups and tribes throughout the region's history.