* Santa Clara de Asís, Cuba: A municipality in Cuba. The primary language spoken in Cuba is Spanish.
* Santa Clara de Asís, Colombia: A municipality in Colombia. The primary language spoken in Colombia is Spanish.
* Santa Clara de Asís Monastery: There are many monasteries with this name around the world. The language spoken would depend on the location of the monastery. For example, the Santa Clara de Asís Monastery in Spain would use Spanish, while the Santa Clara de Asís Monastery in Italy would use Italian.
To give you a more specific answer, please clarify which "Santa Clara de Asis" you are referring to.