1. John Milton's *Areopagitica* (1644): This impassioned plea for freedom of the press and expression remains a cornerstone of modern liberalism and is widely considered one of the most important arguments for free speech in history. Its influence can be seen in the development of modern democratic ideals and the right to freedom of speech in many countries.
2. John Locke's *Two Treatises of Government* (1689): Locke's treatise laid the foundation for modern political philosophy and greatly influenced the American and French revolutions. His ideas of natural rights, limited government, and individual liberty remain central to modern political discourse.
3. Thomas Hobbes's *Leviathan* (1651): Hobbes's treatise, a defense of absolute monarchy, sparked debate and influenced political thought for centuries. It explored the nature of power and social order, laying the groundwork for social contract theory and influencing subsequent political philosophers like Rousseau and Kant.
4. Francis Bacon's *Novum Organum* (1620): Bacon's influential work promoted a scientific approach to knowledge based on observation and experimentation. It marked a turning point in intellectual history and significantly impacted the development of modern science.
5. The King James Bible (1611): While a translation, the King James Bible's influence on English prose is undeniable. Its beautiful and rhythmic language influenced countless writers and poets throughout the centuries, shaping the very language we speak today.
These are just a few examples, and the 17th century saw the emergence of many other influential writers and works. Ultimately, the "most influential" prose depends on what criteria you consider most important. The influence of these works is undeniable, however, and they continue to shape our understanding of the world and ourselves.