* If you're referring to women in general: The most common translation is "signore" (pronounced seen-yore), which is the plural form of "signora" (lady).
* If you're being more formal: You can use "le signore" (lay seen-yore), which is the feminine plural of "il signore" (gentleman).
* If you're using it in a specific context, like addressing a group of women: You could use "donne" (don-nay), which simply means "women".
So, the best translation depends on the situation!