Here are some examples:
* Mi hermana es la mayor. (My sister is the oldest.)
* Mi hermana es la más inteligente. (My sister is the most intelligent.)
* Mi hermana es la que cocina mejor. (My sister is the one who cooks best.)
* Mi hermana es la que vive en Madrid. (My sister is the one who lives in Madrid.)
Please tell me what you want to say after "la" and I can give you a more precise translation!