Here are some examples of how you could answer "de quién es," depending on the context:
If you're talking about a specific object:
* "Es de Juan." (It's Juan's.)
* "Es de mi hermana." (It's my sister's.)
* "Es de la escuela." (It's the school's.)
* "Es mío/mía." (It's mine.)
If you're talking about a person's possession or characteristic:
* "La inteligencia es de su padre." (The intelligence is from his father.)
* "El talento para el arte es de su madre." (The talent for art is from his mother.)
If you're talking about something abstract:
* "La idea es de mi amigo." (The idea is from my friend.)
* "El plan es del gerente." (The plan is from the manager.)
If you don't know who it belongs to:
* "No lo sé." (I don't know.)
* "No tengo idea." (I have no idea.)
To give you the most appropriate answer, please provide more context about what you are referring to.