Here are a few ways to translate it correctly:
* What is Manolo like? - This is the most direct translation and works if you are asking about Manolo's personality or characteristics.
* How is Manolo? - This is a more general question asking about Manolo's current state or well-being.
* How is Manolo doing? - Another way to ask about Manolo's current situation or well-being.
The original phrase "como es manolo" is a bit awkward in Spanish, so if you want to sound more natural, you should use one of the corrected versions.