It's a common phrase used to express disagreement or denial. It's a more emphatic way of saying "no" or "that's not true".
Here's a breakdown:
* En: This is a prefix that indicates emphasis.
* Se: This is a conjunction that means "that" or "that it is".
* Ye: This is the negative particle, equivalent to "not".
Therefore, "en-se-ye" literally translates to "It is not that".
Let me know if you have any other Twi phrases you'd like to understand!