It's likely you're thinking of words that end with "-gue" in Spanish or French, where it *does* have a specific meaning. In both languages, "-gue" often indicates a silent "e" at the end of a word.
Examples:
* Spanish: "lengua" (tongue), "sigue" (follows), "fatigue" (fatigue)
* French: "fatigue" (fatigue), "vogue" (fashion), "rogue" (rogue)
In these cases, the "-gue" is part of the spelling convention for these words and doesn't convey a separate meaning.
If you provide more context or the specific word you're looking at, I might be able to provide a more precise explanation.