Simple:
* The mechanic made a small modification to the car's engine.
* The artist made a few modifications to their original design.
More complex:
* The company implemented modifications to their safety protocols after the accident.
* The professor suggested modifications to the student's research proposal.
* After a few modifications, the website finally looked the way I wanted it to.
* The author made some modifications to the book's ending before publishing.
Figurative:
* The new CEO brought about a modification in the company's culture.
* Time has a way of making modifications to our perspectives.
The specific use of "modification" will depend on the context and the intended meaning.