Based on the meaning of change:
* Stagnation: This implies a lack of change or development.
* Immobility: This refers to a state of being unable to move or change.
* Inertia: This describes a resistance to change or movement.
Based on the meaning of adjustment:
* Resistance: This suggests an unwillingness or inability to adjust.
* Rejection: This refers to the act of refusing to accept something new.
* Inflexibility: This implies a lack of ability to change or bend to different situations.
Based on the meaning of fitting in:
* Isolation: This suggests a state of being separate or apart from others.
* Exclusion: This refers to being kept out or excluded from something.
* Alienation: This describes a feeling of estrangement or separation.
Other possible antonyms:
* Originality: If "adaptation" refers to a derivative work, the antonym could be "originality."
* Uniqueness: Similar to "originality," this refers to something being one of a kind.
The most accurate antonym will depend on the specific context in which "adaptation" is used.