As a verb:
* The compass helped us orient ourselves in the forest. (meaning: to find our position and direction)
* The teacher oriented the students to the new curriculum. (meaning: to familiarize with something)
* She oriented her desk to face the window. (meaning: to position or align)
As an adjective:
* The painting had an oriental theme. (meaning: relating to the East)
* He wore an orient pearl necklace. (meaning: lustrous, especially referring to a type of pearl)
As a noun (less common):
* The ancient orient was a source of mystery and intrigue. (meaning: the East, especially Asia)
The best way to use "orient" depends on the context of your sentence. Choose the usage that best fits the meaning you want to convey.