It carries a strong sense of spiritual purity, often used in religious contexts.
Here are some examples of its use:
* Vishudha manas (വിശുദ്ധ മനസ്സ്) - pure heart
* Vishudha jeevitham (വിശുദ്ധ ജീവിതം) - holy life
* Vishudha sthala (വിശുദ്ധ സ്ഥലം) - holy place
It can also be used in a more general sense to describe something clean, uncontaminated, or morally upright.