Here are some possibilities:
* "Well of" as in a source or abundance:
* Empty of: This implies a lack of something. Example: "He was well of money, but now he's empty of funds."
* Poor in: This focuses on the lack of a specific thing. Example: "She was well of experience, but poor in practical skills."
* "Well of" as in a metaphorical sense:
* Deprived of: This implies a lack of something essential. Example: "He was well of hope, but now he's deprived of it."
* Lacks: This is a more general way to express a lack. Example: "She was well of confidence, but now she lacks it."
Without more context, it's impossible to give a single, definitive opposite.
Please provide more information about how "well of" is being used, and I can give you a more specific answer.