General opposites:
* Unassign: This is the most direct opposite, meaning to remove an assignment.
* Defer: To postpone or delay an assignment.
* Reject: To refuse to accept an assignment.
* Decline: To politely refuse an assignment.
Specific opposites based on context:
* Release: If "assign" means to allocate something, "release" could be the opposite, meaning to make something available.
* Disperse: If "assign" means to distribute something, "disperse" could be the opposite, meaning to spread out.
* Remove: If "assign" means to attach something, "remove" could be the opposite, meaning to detach it.
To determine the most accurate opposite, consider the specific situation where "assign" is being used.