Formal:
* De novo: This is the most common and formal way to say "again."
* Novamente: Similar to "de novo," but slightly more formal.
Informal:
* Outra vez: This is the most common informal way to say "again."
* Mais uma vez: This literally means "one more time."
* De novo: This can also be used informally.
Other options:
* Repetir: This means "to repeat," and is used to request someone to say something again.
* Repetidamente: This means "repeatedly," and is used to describe something that happens again and again.
Here are some examples:
* "Can you say that again?" - "Pode repetir?" (formal) or "Pode dizer de novo?" (informal)
* "I'll try again." - "Vou tentar de novo."
* "I did it again." - "Eu fiz de novo."
The best way to choose the right word is to consider the context of the conversation.