General Opposites:
* Ignorant: Lacking knowledge or information.
* Unconscious: Not aware of what's happening around them.
* Insensitive: Not noticing or caring about the feelings of others.
* Unmindful: Not paying attention or being thoughtful.
* Uninformed: Not having been told about something.
* Unaware: This is simply the negative form of "aware."
* Clueless: Completely lacking in knowledge or understanding.
More Specific Opposites:
* Unheeding: Not paying attention to.
* Neglectful: Failing to pay attention or care for something.
* Disregarding: Not paying attention to or taking into consideration.
* Blind: Figuratively unable to see or understand something.
* Inattentive: Not paying attention to what is happening around them.
The best word to use will depend on the specific context and what you want to emphasize.