General synonyms:
* Leave: This is a very basic synonym, simply meaning to depart from a place or thing.
* Desert: This implies leaving someone or something in a difficult or dangerous situation.
* Forsake: This suggests a deliberate act of leaving someone or something behind, often permanently.
* Give up: This refers to ceasing an effort or attempt.
* Relinquish: This implies giving up control or possession of something.
* Renounce: This suggests a formal or public rejection of something.
More specific synonyms:
* Disown: This specifically refers to rejecting a family member or relationship.
* Discard: This implies throwing something away as useless.
* Neglect: This refers to failing to care for something or someone.
* Abdicate: This refers to giving up a position of power.
* Abandon oneself to: This means to give in completely to a feeling or experience.
The best synonym for "abandon" will depend on the specific context of your sentence.