* Medical: "The chronic pain in her back was debilitating, making it difficult for her to walk or even stand for long periods."
* Emotional: "His anxiety was so debilitating that it interfered with his ability to work and maintain healthy relationships."
* Social: "The constant bullying he faced was debilitating, causing him to withdraw from social activities and lose confidence."
* Economic: "The economic downturn had a debilitating effect on small businesses, forcing many to close their doors."
* Environmental: "The drought was debilitating for farmers, destroying crops and causing widespread livestock losses."