Formal:
* Je suis seul(e). (This is the most common and literal translation.)
Informal:
* Je suis tout(e) seul(e). (This emphasizes being completely alone.)
* Je suis seul(e) au monde. (This means "I am alone in the world" and is more poetic.)
More nuanced expressions:
* Je me sens seul(e). (This means "I feel alone" and focuses on the emotional state.)
* Je suis tout(e) seul(e) à penser ça. (This means "I am the only one who thinks this" and implies a sense of isolation.)
Remember to choose the expression that best fits the context and your intended meaning.