Formal:
* Ano po ang ginagawa ninyo? (This is the most polite and formal way to ask.)
Informal:
* Ano'ng ginagawa mo? (This is the most common and casual way to ask.)
* Anong ginagawa mo? (This is a shortened version of the previous one, still informal.)
* Ano ginagawa mo? (Even more informal, this is used among close friends or family.)
* Kumusta ka? (This literally translates to "How are you?", but can be used to mean "What are you doing?")
Note:
* "Po" is a marker of respect, used when addressing someone older or of higher social standing than you.
* "Ninyo" is the polite form of "you" for multiple people.
* "Mo" is the informal form of "you" for one person.
It's best to choose the most appropriate phrase based on the situation and your relationship with the person you are talking to.