Mean: This describes someone who is unkind, selfish, and often enjoys causing others pain.
Dastard: This describes someone who is cowardly and cruel, especially in a treacherous or cowardly way.
Here's an example:
* Mean: A mean child might steal another child's toys.
* Dastard: A dastardly act could be poisoning someone's food.
While someone could be both mean and dastardly, the terms are not interchangeable.