General disdain:
* Scorn
* Disdain
* Derision
* Disrespect
* Disregard
* Abhorrence
* Loathing
* Repugnance
* Aversion
* Hatred
Legal context:
* Contumacy
* Defiance
* Insubordination
* Obstruction
Informal/colloquial:
* Look down on
* Sneer at
* Spit on
* Think nothing of
The best synonym for you will depend on the specific context in which you are using it.