What is the synonym of frailty?

Here are some synonyms for "frailty," depending on the context:

General Weakness:

* Weakness

* Delicacy

* Fragility

* Vulnerability

* Tenebrousness (literary, suggesting a fragile, easily broken state)

Moral Weakness:

* Flaw

* Fault

* Imperfection

* Vice

* Sin

* Infirmity

Physical Weakness:

* Debility

* Infirmity

* Ailment

* Illness

* Disease

Other:

* Ephemerality (short-livedness)

* Transitoriness (impermanence)

The best synonym will depend on the specific context and the meaning you want to convey.