General Antonyms:
* Hinder: To make it difficult for someone to do something.
* Obstruct: To block or prevent movement or progress.
* Impede: To slow or stop the progress of something.
* Hamper: To make it difficult for someone to do something by restricting their movements.
* Thwart: To prevent someone from achieving something.
Specific Antonyms:
* Hurt: To cause pain or damage.
* Abuse: To treat someone badly.
* Reject: To refuse to accept something.
* Ignore: To pay no attention to someone or something.
Other words that convey the opposite meaning of "help":
* Neglect: To fail to take care of someone or something.
* Abandon: To leave someone or something without any help.
* Betray: To act against someone who trusts you.
* Exploit: To take unfair advantage of someone.
The best antonym for "help" will depend on the specific situation.