What is another word for sharpness of mind?

Here are some words that convey the sharpness of mind, depending on the specific nuance you want to express:

General Sharpness:

* Acuity

* Keenness

* Astuteness

* Perceptiveness

* Brightness

* Cleverness

* Intelligence

* Wit

More Specific:

* Ingenuity (creative problem-solving)

* Sagacity (wisdom and good judgment)

* Discernment (ability to distinguish)

* Insight (deep understanding)

* Perspicacity (keen mental vision)

Informal:

* Sharp

* Quick

* Bright

* Smart

The best word will depend on the specific context and the level of formality required.