General:
* Hazardous
* Risky
* Perilous
* Treacherous
* Unsafe
* Threatening
* Harmful
* Precarious
* Unstable
* Insecure
More intense:
* Deadly
* Lethal
* Fatal
* Destructive
* Catastrophic
More specific:
* Explosive (for something that could explode)
* Toxic (for something that is poisonous)
* Infectious (for something that can spread disease)
* Corrosive (for something that can eat away at materials)
* Flammable (for something that can easily catch fire)
The best synonym will depend on the specific situation you're describing.