Formal:
* Disadvantaged
* Deprived
* Impoverished
* Needy
* Marginalized
* Underrepresented
* Underserved
* Economically challenged
Informal:
* Poor
* Less fortunate
* Hard-up
* Down and out
* Struggling
* In need
More specific:
* Low-income (focuses on financial status)
* Working class (focuses on socioeconomic status)
* Minorities (focuses on lack of representation)
* Homeless (focuses on housing situation)
The best synonym to use depends on the specific context and the desired level of formality.