Here are some synonyms for destitute:
* impoverished
* penniless
* needy
* indigent
* begging
* homeless
Here are some examples of how you might use "destitute" in a sentence:
* The earthquake left many people destitute and homeless.
* He was destitute of any hope or ambition.
* She felt destitute after losing her job.
It's important to remember that "destitute" is a strong word that carries a sense of extreme hardship and lack.