Here are some synonyms for "despicable":
* Vile
* Abhorrent
* Loathsome
* Repulsive
* Detestable
* Scoundrelly
* Wicked
Here are some examples of how you might use "despicable" in a sentence:
* The villain's despicable actions shocked the audience.
* I find it despicable how some people treat animals.
* Their despicable lies ruined the company's reputation.