Here are some synonyms for "mishandle" and "botch":
Mishandle:
* Mismanage
* Fumble
* Misinterpret
* Misapply
* Misdirect
* Abuse
Botch:
* Mess up
* Screw up
* Ruin
* Spoil
* Flub
* Bungled
Here are some examples of how these words are used in a sentence:
* "The company mishandled the customer complaint, leading to a public relations disaster."
* "He botched the presentation, forgetting key points and stumbling over his words."
* "She mishandled the delicate instrument, breaking it beyond repair."
* "The construction crew botched the job, leaving the building with leaks and faulty wiring."
Essentially, it means to do something badly, making a situation worse or causing something to fail.