General:
* The surgeon performed a skillful operation, saving the patient's life.
* The artist's skillful use of color created a breathtaking painting.
* Her skillful negotiation skills helped her secure a great deal.
With a noun:
* The pianist's skillful fingers danced across the keys.
* The chef's skillful use of spices created a flavorful dish.
* His skillful maneuvering of the boat through the rough waters impressed everyone.
In a descriptive phrase:
* The team's skillful performance earned them a victory.
* With a skillful flick of the wrist, the magician made the rabbit disappear.
* The athlete's skillful moves allowed her to outrun her opponents.
Remember that "skillful" is an adjective, so it should describe a noun or pronoun. You can also use it as part of a phrase to add detail to your sentence.