If you're talking about humor:
* Serious
* Dull
* Boring
* Unfunny
* Grim
If you're talking about strange or unusual:
* Normal
* Ordinary
* Typical
* Expected
If you're talking about something being amusing or entertaining:
* Unentertaining
* Dull
* Monotonous
* Tedious
To get the most accurate opposite, you need to consider the specific situation where you want to use the word.