General:
* Restless
* Nervous
* Upset
* Disturbed
* Flustered
* Anxious
Stronger:
* Frantic
* Hysterical
* Panicked
* Beside oneself
* In a frenzy
More specific:
* Excited (if the agitation is positive)
* Angry (if the agitation is caused by anger)
* Fearful (if the agitation is caused by fear)
The best synonym will depend on the context of the sentence and the specific emotion you want to convey.