As a noun:
* His constant fidgeting and rapid breathing were signs of his agitation. (Describing a state of nervousness)
* The politician's speech caused agitation among the crowd. (Describing a state of unrest)
* The news of the earthquake caused widespread agitation in the city. (Describing a state of anxiety)
As a verb:
* The protesters agitated for change. (Describing the act of stirring up unrest)
* The news article agitated the public. (Describing the act of provoking a reaction)
* The wind agitated the water, creating choppy waves. (Describing the act of stirring or shaking something)
In a figurative sense:
* The rumors swirling around the scandal only served to further agitate the situation. (Describing how something makes a situation worse)
* Her mind was in a state of agitation, unable to focus on anything. (Describing a state of mental unrest)
The specific meaning of "agitation" will depend on the context of the sentence.