* Simple: The hotel had a vacancy for a single room.
* Descriptive: After the old librarian retired, there was a vacancy at the library that no one seemed qualified to fill.
* Figurative: The recent tragedy left a vacancy in their hearts that could never be filled.
* Formal: The board announced the vacancy of the CEO position and invited applications.
* Informal: My apartment has a vacancy in the roommate situation, are you interested?
The meaning of "vacancy" can vary depending on the context, but it generally refers to an empty space or position that is available to be filled.