To understand what "Que lo" means, you need to see the full sentence or phrase it is part of.
Here are some examples:
* "Que lo disfrutes" - "Enjoy it"
* "Que lo pase bien" - "Have a good time"
* "Que lo sepas" - "You know" or "Just so you know"
* "Que lo hagas con cuidado" - "Do it carefully"
Essentially, "Que lo" is used to emphasize or add a specific tone to the following verb or phrase.
To understand "Que lo" better, you need to see the complete sentence and analyze the context.