* Prefixes: Added to the beginning of a word (e.g., *un-* in *unhappy*).
* Suffixes: Added to the end of a word (e.g., *-ing* in *walking*).
So, to answer your question, you would add prefixes and suffixes to a root word standing alone.
Here are some examples:
Root word: happy
* Prefix: unhappy
* Suffix: happily
Root word: read
* Prefix: re-read
* Suffix: reader
Let me know if you have any other questions!